Skip to main content

What are the requirements for shipping cell lines and temperature-sensitive products?

Updated over 3 weeks ago

Cold chain products require specialised shipping to maintain quality and viability.

Temperature requirements by product type:

Ultra-low (-80°C to -20°C):

  • Frozen cell lines

  • Certain enzymes and proteins

  • Some reagents

Refrigerated (2-8°C):

  • Some growth factors

  • Ready-to-use media

  • Certain supplements

Shipping methods:

Frozen shipments:

  • Pack in validated insulated containers

  • Use sufficient dry ice (typically 2-5 kg per day of transit plus 24-hour buffer)

  • Include temperature indicator cards or data loggers

  • Mark as "Dry Ice - Frozen Biological Material"

  • Ship via express service (24-48 hour delivery)

  • Coordinate delivery timing with buyer

Refrigerated shipments:

  • Use insulated containers with gel packs

  • Include temperature indicators

  • Ship via express or priority service

  • Avoid weekend delivery when possible

Documentation requirements:

Include with cold chain shipments:

  • Certificate of Analysis with storage temperature

  • Temperature indicator status guide

  • Immediate handling instructions

  • Viability guarantee terms

  • Your contact information for immediate temperature excursion reporting

Validation:

Maintain documentation showing:

  • Shipping container validation data

  • Temperature stability during typical transit times

  • Seasonal adjustments to packaging

Delivery coordination:

For high-value or critical cell lines:

  • Email buyer with expected ship date

  • Provide tracking information immediately

  • Request confirmation of receipt

  • Be available to troubleshoot temperature issues

Temperature excursion protocol:

If buyer reports temperature indicator showing excursion:

  • Request photo of temperature indicator

  • Review shipment timeline

  • Assess likely impact on product

  • Offer replacement if quality is compromised

  • Investigate cause to prevent recurrence

Quality guarantee:

Standard practice for cell line suppliers:

  • Guarantee viability if:

    • Temperature indicator shows acceptable range

    • Product opened and used within specifications

    • Handling followed instructions

  • Replace at no charge if:

    • Temperature compromised during shipping

    • Product defective as shipped

    • Viability below specified percentage

Did this answer your question?